Long telomeres of youth encourage optimism
نویسندگان
چکیده
منابع مشابه
The long reach of telomeres.
The primary purpose of telomeres is to protect chromosome ends from erosion during cell division cycles. New observations suggest an additional function for telomeres, namely in gene silencing via formation of long-range chromatin interactions.
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Telomeres and their shortening have been studied in the con text of psychiatric disorders for about 10 years. A number of studies correlating telomere length (TL) with selected psycho pathologies have generated intriguing and largely consistent findings: many psychiatric disorders are associated with shorter leukocyte TL. Yet, this observation can be interpreted in alternative ways, and choos...
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Since ageing is a universal human feature, it is not surprising that, from the Babylonian epic of Gilgamesh to Ponce de Leon seeking the "Fountain of Youth," countless people have dreamed of finding a way to avoid ageing, to no avail. Yet the search continues. In this review, we present one of the latest candidates: the enzyme telomerase, capable of elongating the tips of chromosomes, the telom...
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Dyskeratosis congenita (DC) is an inherited life threatening bone marrow failure syndrome [1]. The name dyskeratosis comes from the classic triad of clinical features nail dystrophy, abnormal skin pigmentation and leucoplakia in patients with DC. However the mortality in DC is primarily due to bone marrow failure and other complications such as pulmonary fibrosis, liver cirrhosis and early onse...
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ژورنال
عنوان ژورنال: The Journal of Experimental Biology
سال: 2021
ISSN: ['1477-9145', '0022-0949']
DOI: https://doi.org/10.1242/jeb.235424